The answer will critically depend on your software, in that if you use Ableton it does not recognise MIDI channel when a VST is hosted by it. Scaler (or any other multi-channel source has to be hosted externally and then the MIDI fed into Ableton.
Otherwise, it’s pretty straightforward.
A key factor is whether you follow the simplest case, and route each of the Scaler channels to a different voicing (either in a multi-timbral synth, or N mono-timbral ones). This means you are relying on Scaler to perform the divisi role, but more importantly any one note can only be played by one synth voice.
If on the other hand you want to route say a C3 note on channel 2 from scaler to more than one voice (so that some note is followed by more than one instrument). You need something which can apply a rule to take the single outbound note from Scaler and then re-route that to 2 destinations.
This then will depend on the capabilities of your DAW or Scaler host (as the case may be). Ableton is maybe 15 years behind other DAW’s in this respect - I could do that on Cakewalk’s Sonar years ago.
I have just started the first video of a series on this topic, as I think there is many things to be done by manipulating and splitting Scalers progressions and songs as well as the divisi activity with multi-channel output.
In my early days with Scaler I experimented with taking the existing progressions and slicing them up horizontally with a ‘rack’ and re-routing them ; I now realise it’s easier and quicker just to apply rules to the MIDI stream, which you can do with the right app…
My post is here
and you can hear a trivial little example (item 3) here
http://starcluster.co.uk/obs/