The trick is very simple
Here is the routing
Then put some chords in EZBass and audit any of its MIDIs to drive AAS Strum-GS 2 in the Keyboard mode; distorted guitars are better, but creamy ones may work also
The syncopation of basslines creates cool riffs, and if you dare mixing styles, e.g. a latin bassline for a rock guitar, the results will be amazing
Then, duplicate the guitar and set the second one in Loop mode to have an accompaniment, add the drums, and here is one of the several possible samples